Disease: Major Depressive Disorder
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
USP46 P62068 ubiquitin specific peptidase 46 Enzyme 0.79 0.769 0.192
TSNAX-DISC1 TSNAX-DISC1 readthrough (NMD candidate) 0.729 0.154
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654
TPH1 P17752 tryptophan hydroxylase 1 3.2E-07 0.553 0.731
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
TDO2 P48775 tryptophan 2,3-dioxygenase Enzyme 2.0E-10 0.599 0.654
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923
SSTR5 P35346 somatostatin receptor 5 G-protein coupled receptor 9.6E-04 0.590 0.615
SST P61278 somatostatin Signaling 0.34 0.399 0.885
SRRT Q9BXP5 serrate, RNA effector molecule 0.59 0.736 0.231
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
SLC6A2 P23975 solute carrier family 6 member 2 Transporter 8.2E-02 0.490 0.846
SLC6A13 Q9NSD5 solute carrier family 6 member 13 Transporter 1.2E-11 0.736 0.346
SLC1A6 P48664 solute carrier family 1 member 6 Transporter 0.76 0.780 0.154
SLC17A6 Q9P2U8 solute carrier family 17 member 6 Transporter 0.16 0.678 0.500
SEC24C P53992 SEC24 homolog C, COPII coat complex component Transporter 1.00 0.543 0.808
SAT1 P21673 spermidine/spermine N1-acetyltransferase 1 0.87 0.539 0.808
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
S100A10 P60903 S100 calcium binding protein A10 Calcium-binding protein 0.17 0.528 0.769
RNF41 Q9H4P4 ring finger protein 41 0.97 0.674 0.538
RELN P78509 reelin 1.00 0.515 0.731
RAPGEF5 Q92565 Rap guanine nucleotide exchange factor 5 Enzyme modulator 0.98 0.524 0.769